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DDX3 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572086
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50-157-2086 10 μL
50-157-2085 100 μL
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Catalog No. 50-157-2086 Supplier Bethyl Laboratories, Inc Supplier No. IHC00431T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Rabbit, Pig, Golden hamster, Panda, Orangutan, Monkey, Gorilla and White-tufted

DDX3 contains all of the motifs of the DEAD-box family of RNA helicases, including the Asp-Glu-Ala-Asp sequence that gives the protein family its name and distinguishes it from other RNA helicases. DDX3 is localized to the X chromosome and has a highly conserved functional homolog (DBY) on the Y chromosome. DDX3 is thought to be involved in RNA splicing, RNA transport, and translation initiation. It has also been shown to be involved in cell growth control and is deregulated in hepatitis virus-associated hepatocellular carcinoma. Recent experiments suppressing DDX3 expression blocked HIV-1 RNA export from the nucleus, suggesting that DDX3 functions as a shuttling protein that transports the HIV-1 protein Rev and its cofactor CRM1 from the nucleus to the cytoplasm.

Specifications

Antigen DDX3
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene DDX3X
Gene Accession No. O00571, Q62167
Gene Alias DEAD box protein 3, X-chromosomal; Helicase-like protein 2; HLP2; DEAD box; X isoform; DDX3X; DBX
Gene Symbols DDX3X
Host Species Rabbit
Immunogen Between 1 and 50
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13205, 1654
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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