Invitrogen™ DDX39 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531220

Catalog No. PIPA531220

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Rat (98%), Xenopus laevis (95%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Specifications

• Antigen: DDX39
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DDX39A
• Gene Alias: 2610307C23Rik; ATP-dependent RNA helicase DDX39; ATP-dependent RNA helicase DDX39A; BAT1; BAT1L; DDX39; Ddx39a; Ddxl; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; DEAD box protein 39; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39; DEAD-box helicase 39A; nuclear RNA helicase URH49; Nuclear RNA helicase, DECD variant of DEAD box family; UAP56-related helicase, 49 kDa; URH49
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10212
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.64 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O00148
• Gene Symbols: DDX39A
• Immunogen: Recombinant fragment corresponding to a region within amino acids 229 and 427 of Human DDX39.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov