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DDX4/VASA Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501735866 Shop All Proteintech Group Inc Products
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Catalog No. 50-173-5866 Supplier Proteintech Group Inc Supplier No. 510421AP150UL
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Rabbit Polyclonal Antibody

DDX4 belongs to the DEAD box helicase family or DDX4/VASA subfamily. DEAD box proteins are characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif and are putative RNA helicases. This protein has a glycine-rich N terminus with multiple repeats of an RGG motif, which is believed to function in RNA binding. They have a role in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. The members of this family are involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila. It is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. It is required during gametogenesis in the adult and in the specification of the germ cell lineage during embryogenesis. This is conserved in invertebrate and vertebrate species.

Specifications

Antigen DDX4/VASA
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene DDX4
Gene Accession No. Q61496, Q9NQI0
Gene Alias DDX4, DEAD box protein 4, VASA, Vasa homolog
Gene Symbols DDX4
Host Species Rabbit
Immunogen DDX4,VASA Fusion Protein Ag0447
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13206, 54514
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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