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Invitrogen™ DDX50 Polyclonal Antibody
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Catalog No. PIPA541294
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100 μL
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PIPA541294 100 μL
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Catalog No. PIPA541294 Supplier Invitrogen™ Supplier No. PA541294
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Description

Rabbit Polyclonal Antibody

Peptide sequence: EESESQKKER QKSDRRKSRH HYDSDEKSET RENGVTDDLD APKAKKSKMK Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Pig: 93%; Rabbit: 100%.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX50 is a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. DDX50 and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. DDX50 gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DDX50
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene DDX50
Gene Accession No. Q9BQ39
Gene Alias 4933429B04Rik; 8430408E17Rik; ATP-dependent RNA helicase DDX50; ATP-dependent RNA helicase DDX50-like protein; Ddx50; DEAD (Asp-Glu-Ala-Asp) box polypeptide 50; DEAD box protein 50; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 50; DEAD-box helicase 50; DExD-box helicase 50; GU2; GUB; Gubeta; gu-beta; malignant cell derived RNA helicase; mcdrh; Nucleolar protein Gu2; RH-II; RH-II/GuB; RH-II/Gubeta; RNA helicase II/Gu beta; Unknown (protein for IMAGE:8120580)
Gene Symbols DDX50
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human DDX50 (aa 18-67).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79009
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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