Invitrogen™ DDX60L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560278

Catalog No. PIPA560278

Description

Immunogen sequence: QEPHLNLGDS IRRDYEDLWN VVSHLVKEFN LGKSFPLRTT RRHFLRQEKS VIQEISLEKM PSVGFIPMTS AVIDEFVGDM MKDL Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 48%.

This gene encodes a member of the DExD/H-box helicase family of proteins, a subset of the super family 2 helicases. Members of the DExD/H-box helicase family share a conserved functional core comprised of two RecA-like globular domains. These domains contain conserved motifs that mediate ATP binding, ATP hydrolysis, nucleic acid binding, and RNA unwinding. In addition to functions in RNA metabolism, members of this family are involved in anti-viral immunity and act as cytosolic sensors of viral nucleic acids. The protein encoded by this gene has been shown to inhibit hepatitis C virus replication in response to interferon stimulation in cell culture. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: DDX60L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DDX60L
• Gene Alias: DDX60L; DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like; DEAD box protein 60-like; DEAD-box helicase 60-like; probable ATP-dependent RNA helicase DDX60-like; putative ATP-dependent RNA helicase DDX60
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 91351
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5H9U9
• Gene Symbols: DDX60L
• Immunogen: Recombinant protein corresponding to Human DDX60L. Recombinant protein control fragment (Product #RP-96766).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG