Invitrogen™ DECR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120571

Catalog No. PIPA5120571

Description

Positive test controls include: HeLa, Mouse liver, Rat liver, Rat kidney. Immunogen sequence: GTFNVSRVLY EKFFRDHGGV IVNITATLGN RGQALQVHAG SAKAAVDAMT RHLAVEWGPQ NIRVNSLAPG PISGTEGLRR LGGPQASLST KVTASPLQRL G.

DECR2 (2, 4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2, 4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2, 4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2, 4, 7, 10, 13, 16, 19-docosaheptaenoyl-CoA and short and medium chain 2, 4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events.

Specifications

• Antigen: DECR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DECR2
• Gene Alias: 2,4-dienoyl CoA reductase 2, peroxisomal; 2,4-dienoyl-CoA reductase 2; 2,4-dienoyl-CoA reductase 2, peroxisomal; 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal; Dcrakl; DCR-AKL; Decr2; Pdcr; Peroxisomal 2,4-dienoyl-CoA reductase; putative peroxisomal 2,4-dienoyl-CoA reductase; putative peroxisomal 24-dienoyl-CoA reductase; putativeperoxisomal24-dienoyl-CoAreductase; pVI-AKL; SDR17C1; Short chain dehydrogenase/reductase family 17C member 1; short chain dehydrogenase/reductase family 17C, member 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26063, 26378, 64461
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.48 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9NUI1, Q9WV68, Q9Z2M4
• Gene Symbols: DECR2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DECR2 (NP_065715.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG