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Invitrogen™ DECR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550080

Catalog No. PA550080


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Description

Description

The antibody detects endogenous levels of total DECR2 protein.

DECR2 (2, 4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2, 4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2, 4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2, 4, 7, 10, 13, 16, 19-docosaheptaenoyl-CoA and short and medium chain 2, 4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DECR2
Polyclonal
Unconjugated
DECR2
2,4-dienoyl CoA reductase 2, peroxisomal; 2,4-dienoyl-CoA reductase 2; 2,4-dienoyl-CoA reductase 2, peroxisomal; 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal; Dcrakl; DCR-AKL; Decr2; Pdcr; Peroxisomal 2,4-dienoyl-CoA reductase; putative peroxisomal 2,4-dienoyl-CoA reductase; putative peroxisomal 24-dienoyl-CoA reductase; putativeperoxisomal24-dienoyl-CoAreductase; pVI-AKL; SDR17C1; Short chain dehydrogenase/reductase family 17C member 1; short chain dehydrogenase/reductase family 17C, member 1
Rabbit
Antigen affinity chromatography
RUO
26063, 26378
-20°C
Liquid
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9NUI1, Q9WV68
DECR2
Synthesized peptide derived from internal of human DECR2.
100 μL
Primary
Human, Mouse
Antibody
IgG
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