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  6. Invitrogen™ Dectin 1 (soluble) Monoclonal Antibody (2A11), FITC

Invitrogen™ Dectin 1 (soluble) Monoclonal Antibody (2A11), FITC
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Catalog No. PIMA516479
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PIMA516479 100 μg
PIMA516480 50 μg
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Catalog No. PIMA516479 Supplier Invitrogen™ Supplier No. MA516479
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Description

Rat Monoclonal Antibody

For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Rat anti Mouse Dectin-1 antibody, clone 2A11 recognizes murine beta-glucan receptor, also known as Dectin-1. Rat anti Mouse Dectin-1 antibody, clone 2A11 recognizes murine beta-glucan receptor, also known as Dectin-1.

CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Dectin 1 (soluble)
Applications Flow Cytometry
Classification Monoclonal
Clone 2A11
Concentration 0.1 mg/mL
Conjugate FITC
Formulation PBS with 1% BSA and 0.09% sodium azide
Gene Clec7a
Gene Accession No. Q6QLQ4
Gene Alias Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082
Gene Symbols Clec7a
Host Species Rat
Immunogen Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56644
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b
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