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Invitrogen™ DEFA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5117076

Catalog No. PIPA5117076


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Description

Description

Positive Samples: Mouse spleen Immunogen sequence: MRTLAILAAI LLVALQAQAE PLQARADEVA AAPEQIAADI PEVVVSLAWD ESLAPKHPGS RKNMACYCRI PACIAGERRY GTCIYQGRLW AFCC.

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DEFA1
Polyclonal
Unconjugated
DEFA1
alpha-defensin 1; Cryptdin-1; DEF1; Defa1; DEFA1B; DEFA2; Defcr; Defcr1; defensin alpha 1; defensin related cryptdin peptide 1; defensin, alpha 1; defensin, alpha 1, myeloid-related sequence; defensin, alpha 2; defensin-1; defensin-related cryptdin peptide; HNP-1; HNP-2; HP 1-56; HP1; HP-1; HP-2; MRS; myeloid-related sequence; neutrophil defensin 1; Neutrophil defensin 2
Rabbit
Affinity Chromatography
RUO
13216, 1667
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot, Immunocytochemistry
0.40 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P11477, P59665
DEFA1
A synthetic peptide corresponding to a sequence within amino acids 1-94 of human DEFA1 (NP_0040751).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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