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Invitrogen™ DEFA4 Polyclonal Antibody
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Catalog No. PIPA5103124
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Quantity:
100 μL
Catalog No. Quantity
PIPA5103124 100 μL
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Catalog No. PIPA5103124

Supplier: Invitrogen™ PA5103124

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Defensin alpha 4.

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DEFA4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DEFA4
Gene Accession No. P12838, P28311
Gene Alias Alpha-defensin 4; corticostatin; Crp4; DEF4; Defa28; Defa4; Defcr4; defensin alpha 4; Defensin, alpha 4; defensin, alpha 4, corticostatin; defensin, alpha 4, preproprotein; defensin, alpha, 4; Defensin-related cryptdin-4; HNP-4; HP4; HP-4; Neutrophil defensin 4
Gene Symbols DEFA4
Host Species Rabbit
Immunogen A synthesized peptide derived from human DEFA4(Accession P12838), corresponding to amino acid residues I3-A53.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13238, 1669
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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