Invitrogen™ DEFB132 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561233

Catalog No. PIPA561233

Description

Immunogen sequence: PGYCRTCCHW GETALFMCNA SRKCCISYSF LPKPDLPQLI GNHWQSRRRN TQRKDKKQQT TVTS Highest antigen sequence identity to the following orthologs: Mouse - 28%, Rat - 28%.

Beta-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, beta-defensins are developmentally regulated. The family of beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many beta-defensins also are involved in sperm maturation and capacitation. beta-defensin 32, also known as beta-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.

Specifications

• Antigen: DEFB132
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEFB132
• Gene Alias: BD-32; Beta-defensin 132; beta-defensin 32; DEFB132; DEFB32; DEFB-32; defensin beta 132; defensin HEL-75; Defensin, beta 132; defensin, beta 32; HEL-75; KFLL827; RP5-1103G7.6; UNQ827; UNQ827/PRO1754
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 400830
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7Z7B7
• Gene Symbols: DEFB132
• Immunogen: Recombinant protein corresponding to Human DEFB132. Recombinant protein control fragment (Product #RP-99472).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG