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Invitrogen™ DEFB132 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA561233
Description
Immunogen sequence: PGYCRTCCHW GETALFMCNA SRKCCISYSF LPKPDLPQLI GNHWQSRRRN TQRKDKKQQT TVTS Highest antigen sequence identity to the following orthologs: Mouse - 28%, Rat - 28%.
Beta-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, beta-defensins are developmentally regulated. The family of beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many beta-defensins also are involved in sperm maturation and capacitation. beta-defensin 32, also known as beta-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.
Specifications
DEFB132 | |
Polyclonal | |
Unconjugated | |
DEFB132 | |
BD-32; Beta-defensin 132; beta-defensin 32; DEFB132; DEFB32; DEFB-32; defensin beta 132; defensin HEL-75; Defensin, beta 132; defensin, beta 32; HEL-75; KFLL827; RP5-1103G7.6; UNQ827; UNQ827/PRO1754 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
400830 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin) | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q7Z7B7 | |
DEFB132 | |
Recombinant protein corresponding to Human DEFB132. Recombinant protein control fragment (Product #RP-99472). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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