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Invitrogen™ Defensin 1/3 Polyclonal Antibody
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Catalog No. PIPA519228
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100 μg
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Catalog No. Quantity
PIPA519228 100 μg
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Catalog No. PIPA519228 Supplier Invitrogen™ Supplier No. PA519228
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Defensin 1/3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene DEFA1
Gene Accession No. P59665, P59666
Gene Alias alpha-defensin 1; Alpha-defensin 3; cryptdin-1; DEF1; DEF3; Defa1; DEFA1B; DEFA2; Defa27; Defa3; Defcr; Defcr1; Defcr3; Defcr-3; defensin 3, neutrophil-specific; defensin alpha 1; defensin alpha 3; defensin related cryptdin peptide 1; defensin, alpha 1; defensin, alpha 1, myeloid-related sequence; defensin, alpha 2; Defensin, alpha 3; defensin, alpha 3, neutrophil-specific; defensin, alpha, 27; defensin, alpha, 3; defensin-1; defensin-related cryptdin peptide; Defensin-related cryptdin-3; HNP-1; HNP-2; HNP3; HNP-3; HP 1-56; HP 3-56; HP1; HP-1; HP-2; HP3; HP-3; MRS; myeloid-related sequence; neutrophil defensin 1; Neutrophil defensin 2; Neutrophil defensin 3; neutrophil peptide 3
Gene Symbols DEFA1, DEFA3
Host Species Goat
Immunogen Synthetic peptide sequence (DESLAPKHPGSRKN) corresponding to the internal amino acids of DEFA1/3.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1667, 1668
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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