Invitrogen™ Defensin 1/3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA519228

Catalog No. PIPA519228

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Specifications

• Antigen: Defensin 1/3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEFA1
• Gene Alias: alpha-defensin 1; Alpha-defensin 3; cryptdin-1; DEF1; DEF3; Defa1; DEFA1B; DEFA2; Defa27; Defa3; Defcr; Defcr1; Defcr3; Defcr-3; defensin 3, neutrophil-specific; defensin alpha 1; defensin alpha 3; defensin related cryptdin peptide 1; defensin, alpha 1; defensin, alpha 1, myeloid-related sequence; defensin, alpha 2; Defensin, alpha 3; defensin, alpha 3, neutrophil-specific; defensin, alpha, 27; defensin, alpha, 3; defensin-1; defensin-related cryptdin peptide; Defensin-related cryptdin-3; HNP-1; HNP-2; HNP3; HNP-3; HP 1-56; HP 3-56; HP1; HP-1; HP-2; HP3; HP-3; MRS; myeloid-related sequence; neutrophil defensin 1; Neutrophil defensin 2; Neutrophil defensin 3; neutrophil peptide 3
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 1667, 1668
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P59665, P59666
• Gene Symbols: DEFA1, DEFA3
• Immunogen: Synthetic peptide sequence (DESLAPKHPGSRKN) corresponding to the internal amino acids of DEFA1/3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG