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Defensin 1/3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984046
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50-198-4046 100 μL
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Catalog No. 50-198-4046 Supplier Bioss Supplier No. BS1697R
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Description

Rabbit Polyclonal Antibody

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Specifications

Antigen Defensin 1/3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene DEFA3
Gene Accession No. P59665, P59666
Gene Alias Alpha-defensin 1; Alpha-defensin 3; Cryptdin-1; DEF1; DEF3; Defa1; DEFA1B; DEFA2; Defa27; Defa3; Defcr; Defcr1; Defcr3; Defcr-3; defensin 3, neutrophil-specific; defensin alpha 1; defensin alpha 3; defensin related cryptdin peptide 1; Defensin, alpha 1; defensin, alpha 1, myeloid-related sequence; defensin, alpha 2; Defensin, alpha 3; defensin, alpha 3, neutrophil-specific; defensin, alpha, 27; defensin, alpha, 3; defensin-1; Defensin-related cryptdin peptide; Defensin-related cryptdin-3; HNP-1; HNP-2; HNP3; HNP-3; HP 1-56; HP 3-56; HP1; HP-1; HP-2; HP3; HP-3; MRS; myeloid-related sequence; Neutrophil defensin 1; Neutrophil defensin 2; Neutrophil defensin 3; neutrophil peptide 3
Gene Symbols DEFA1, DEFA3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human alpha Defensin 1/3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1667, 1668
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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