Invitrogen™ Defensin alpha-3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119080

Catalog No. PIPA5119080

Description

Defensin alpha-3 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Defensin alpha-1 is part of a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. Defensins are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The Defensin alpha-1 protein is encoded by the DFA1 gene and is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8, and this gene differs from defensin, alpha 3 by only one amino acid. The DFA1 gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. Two transcript variants encoding different isoforms of Defensin alpha-1 have been found.

Specifications

• Antigen: Defensin alpha-3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEFA3
• Gene Alias: DEF3; DEFA3; defensin 3, neutrophil-specific; defensin alpha 3; Defensin, alpha 3; defensin, alpha 3, neutrophil-specific; HNP-2; HNP3; HNP-3; HP 3-56; HP-2; HP3; HP-3; Neutrophil defensin 2; Neutrophil defensin 3; neutrophil peptide 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1668
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.92 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P59666
• Gene Symbols: DEFA3
• Immunogen: Recombinant protein Defensin Alpha 3, Neutrophil Specific. The antigen corresponds to amino acid range 21-94 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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