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Invitrogen™ Defensin alpha-3 Polyclonal Antibody
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Catalog No. PIPA567958
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100 μL
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PIPA567958 100 μL
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Catalog No. PIPA567958 Supplier Invitrogen™ Supplier No. PA567958
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Description

Rabbit Polyclonal Antibody

Defensin alpha-3 Polyclonal Antibody for Western Blot, IHC, IHC (P)

Defensin alpha-1 is part of a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. Defensins are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The Defensin alpha-1 protein is encoded by the DFA1 gene and is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8, and this gene differs from defensin, alpha 3 by only one amino acid. The DFA1 gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. Two transcript variants encoding different isoforms of Defensin alpha-1 have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Defensin alpha-3
Applications Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol, 0.87% NaCl and 0.01% sodium azide; pH 7.3
Gene DEFA3
Gene Accession No. P59666
Gene Alias DEF3; DEFA3; defensin 3, neutrophil-specific; defensin alpha 3; Defensin, alpha 3; defensin, alpha 3, neutrophil-specific; HNP-2; HNP3; HNP-3; HP 3-56; HP-2; HP3; HP-3; Neutrophil defensin 2; Neutrophil defensin 3; neutrophil peptide 3
Gene Symbols DEFA3
Host Species Rabbit
Immunogen Synthesized peptide derived from human Defensin.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1668
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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