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Defensin alpha 4 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984975
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50-198-4975 100 μL
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Catalog No. 50-198-4975 Supplier Bioss Supplier No. BS2799R
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Description

Rabbit Polyclonal Antibody

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.

Specifications

Antigen Defensin alpha 4
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene DEFA4
Gene Accession No. P12838
Gene Alias Alpha-defensin 4; corticostatin; Crp4; DEF4; Defa28; Defa4; Defcr4; defensin alpha 4; Defensin, alpha 4; defensin, alpha 4, corticostatin; defensin, alpha 4, preproprotein; defensin, alpha, 4; Defensin-related cryptdin-4; HNP-4; HP4; HP-4; Neutrophil defensin 4
Gene Symbols DEFA4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Defensin alpha 4.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1669
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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