Invitrogen™ DEGS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588680

Catalog No. PIPA588680

Description

Immunogen sequence: YMFLKGHETY SYYGPLNLLT FNVGYHNEHH DFPNIPGKSL PLVRKIAAEY YDNLPHYNSW IKVLYDFVMD DTISPYSRMK RHQKGEMVLE; Positive Samples: HeLa, A-549, 293T; Cellular Location: Endoplasmic reticulum membrane, Lipid-anchor, Membrane, Mitochondrion, Multi-pass membrane protein.

The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4 ) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulation biosynthetic processing of the EGF receptor. Two splice variants have been identified.

Specifications

• Antigen: DEGS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEGS1
• Gene Alias: AA536663; Cell migration-inducing gene 15 protein; Degenerative spermatocyte homolog 1; degenerative spermatocyte homolog 1 (Drosophila); degenerative spermatocyte homolog 1, lipid desaturase; degenerative spermatocyte homolog, lipid desaturase; degenerative spermatocyte-like protein RDES; Degs; DEGS1; DEGS-1; delta 4-desaturase, sphingolipid 1; Delta(4)-desaturase; delta(4)-desaturase, sphingolipid 1; DES1; Des-1; dihydroceramide desaturase; dihydroceramide desaturase 1; dihydroceramide desaturase-1; DSH1; FADS7; fb81d06; hypothetical protein LOC507290; im:6909319; Mdes; membrane fatty acid (lipid) desaturase; membrane lipid desaturase; MGC5079; MIG15; migration-inducing gene 15 protein; MLD; sphingolipid 1; sphingolipid delta 4 desaturase; sphingolipid delta(4)-desaturase 1; sphingolipid delta(4)-desaturase DES1; wu:fa25h01; wu:fb81d06
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8560
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O15121
• Gene Symbols: DEGS1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 234-323 of human DEGS1 (NP_0036671).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG