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Invitrogen™ DELE Polyclonal Antibody
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Catalog No. PIPA534403
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100 μg
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Catalog No. Quantity
PIPA534403 100 μg
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Catalog No. PIPA534403 Supplier Invitrogen™ Supplier No. PA534403
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Rabbit Polyclonal Antibody

A suggested positive control is rat brain tissue lysate. PA5-34403 can be used with blocking peptide PEP-1445.

DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-Alpha and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-Alpha, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DELE
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Dele1
Gene Accession No. Q14154
Gene Alias 0610009O20Rik; 2700004E22Rik; DAP3-binding cell death enhancer 1; Death ligand signal enhancer; Dele; Dele1; KIAA0141; RIKEN cDNA 0610009O20 gene
Gene Symbols Dele1
Host Species Rabbit
Immunogen An 18 amino acid synthetic peptide near the amino terminus of human DELE.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9812
Target Species Human, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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