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Demethylasterriquinone B1, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
5mg
This item is not returnable. View return policy
78860-34-1
C32H30N2O4
506.602
XMGNJVXBPZAETK-UHFFFAOYSA-N
demethylasterriquinone b1,dmaq-b1,daq b1,2,5-dihydroxy-3-7-3-methyl-but-2-enyl-1h-indol-3-yl-6-2-1,1-dimethyl-allyl-1h-indol-3-yl-1,4 benzoquinone,2-2-1,1-dimethylallyl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methylbut-2-enyl-1h-indol-3-yl 1,4 benzoquinone,tocris-1819,2,5-cyclohexadiene-1,4-dione, 2-2-1,1-dimethyl-2-propenyl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methyl-2-butenyl-1h-indol-3-yl,2,5-cyclohexadiene-1,4-dione,2-2-1,1-dimethyl-2-propen-1-yl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methyl-2-buten-1-yl-1h-indol-3-yl,2,5-dihydroxy-3-2-2-methylbut-3-en-2-yl-1h-indol-3-yl-6-7-3-methylbut-2-enyl-1h-indol-3-yl cyclohexa-2,5-diene-1,4-dione,2,5-dihydroxy-3-7-3-methylbut-2-en-1-yl-1h-indol-3-yl-6-2-2-methylbut-3-en-2-yl-1h-indol-3-yl cyclohexa-2,5-diene-1,4-dione
3013166
2,5-dihydroxy-3-[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]-6-[7-(3-methylbut-2-enyl)-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dione
CC(=CCC1=CC=CC2=C1NC=C2C3=C(C(=O)C(=C(C3=O)O)C4=C(NC5=CC=CC=C54)C(C)(C)C=C)O)C
This item is not returnable. View return policy
78860-34-1
C32H30N2O4
506.602
XMGNJVXBPZAETK-UHFFFAOYSA-N
demethylasterriquinone b1,dmaq-b1,daq b1,2,5-dihydroxy-3-7-3-methyl-but-2-enyl-1h-indol-3-yl-6-2-1,1-dimethyl-allyl-1h-indol-3-yl-1,4 benzoquinone,2-2-1,1-dimethylallyl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methylbut-2-enyl-1h-indol-3-yl 1,4 benzoquinone,tocris-1819,2,5-cyclohexadiene-1,4-dione, 2-2-1,1-dimethyl-2-propenyl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methyl-2-butenyl-1h-indol-3-yl,2,5-cyclohexadiene-1,4-dione,2-2-1,1-dimethyl-2-propen-1-yl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methyl-2-buten-1-yl-1h-indol-3-yl,2,5-dihydroxy-3-2-2-methylbut-3-en-2-yl-1h-indol-3-yl-6-7-3-methylbut-2-enyl-1h-indol-3-yl cyclohexa-2,5-diene-1,4-dione,2,5-dihydroxy-3-7-3-methylbut-2-en-1-yl-1h-indol-3-yl-6-2-2-methylbut-3-en-2-yl-1h-indol-3-yl cyclohexa-2,5-diene-1,4-dione
3013166
2,5-dihydroxy-3-[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]-6-[7-(3-methylbut-2-enyl)-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dione
CC(=CCC1=CC=CC2=C1NC=C2C3=C(C(=O)C(=C(C3=O)O)C4=C(NC5=CC=CC=C54)C(C)(C)C=C)O)C

Selective insulin RTK activator

Selective insulin receptor (IR) activator (EC50 values are 3 - 6 μM for IRTK and 100 μM for IGF1R and EGFR). Increases IR β subunit tyrosine phosphorylation and activation of PI 3-kinase and Akt, but not ERK. Induces glucose uptake in adipocytes and skeletal muscle in vitro, without enhancing vascular proliferation. Binds GAPDH. Also activates Trk by interacting at a site distinct from the neurotrophin-binding site.

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Quantity 5mg
Formula Weight 506.59
Percent Purity >98%
Chemical Name or Material Demethylasterriquinone B1

Recommended Storage : Desiccate at -20°C