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Invitrogen™ DENND1B Polyclonal Antibody
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Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521824

Catalog No. PIPA521824


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Description

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Clathrin (see MIM 118955)-mediated endocytosis is a majormechanism for internalization of proteins and lipids. Members ofthe connecdenn family, such as DENND1B, function as guaninenucleotide exchange factors (GEFs) for the early endosomal smallGTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptorprotein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35activation with the clathrin machinery.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DENND1B
Polyclonal
Unconjugated
DENND1B
4632404N19Rik; 4930467M19Rik; 6820401H01Rik; ASL1/9AS1-1 fusion; C1ORF18; C1orf218; Connecdenn 2; DENN domain containing 1B; DENN domain-containing protein 1B; DENN/MADD domain containing 1B; Dennd1b; F730008N07Rik; Fam31b; family with sequence similarity 31, member B; Protein FAM31B; RP11-53I24.2
Rabbit
Antigen affinity chromatography
RUO
163486, 329260
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry
0.9 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q3U1T9, Q6P3S1
DENND1B
Recombinant protein encompassing a sequence within the center region of human DENND1B. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse
Antibody
IgG
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