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Invitrogen™ DENND1B Polyclonal Antibody
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Catalog No. PIPA521824
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100 μL
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PIPA521824 100 μL
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Catalog No. PIPA521824 Supplier Invitrogen™ Supplier No. PA521824
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Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Clathrin (see MIM 118955)-mediated endocytosis is a majormechanism for internalization of proteins and lipids. Members ofthe connecdenn family, such as DENND1B, function as guaninenucleotide exchange factors (GEFs) for the early endosomal smallGTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptorprotein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35activation with the clathrin machinery.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DENND1B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene DENND1B
Gene Accession No. Q3U1T9, Q6P3S1
Gene Alias 4632404N19Rik; 4930467M19Rik; 6820401H01Rik; ASL1/9AS1-1 fusion; C1ORF18; C1orf218; Connecdenn 2; DENN domain containing 1B; DENN domain-containing protein 1B; DENN/MADD domain containing 1B; Dennd1b; F730008N07Rik; Fam31b; family with sequence similarity 31, member B; Protein FAM31B; RP11-53I24.2
Gene Symbols DENND1B
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human DENND1B. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 163486, 329260
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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