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Invitrogen™ DENND1C Polyclonal Antibody
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Catalog No. PIPA560105
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100 μL
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PIPA560105 100 μL
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Catalog No. PIPA560105 Supplier Invitrogen™ Supplier No. PA560105
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Rabbit Polyclonal Antibody

Immunogen sequence: PSPPESPQIL APTKPNFDIA WTSQPLDPSS DPSSLEDPRA RPPKALLAER AHLQPREEPG ALNSPATPTS NCQKSQPSSR PRVADLKKCF E Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 45%.

Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DENND1C
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DENND1C
Gene Accession No. Q8IV53
Gene Alias Connecdenn 3; DENN domain containing 1C; DENN domain-containing protein 1C; DENN/MADD domain containing 1C; DENND1C; FAM31C; family with sequence similarity 31, member C; Protein FAM31C
Gene Symbols DENND1C
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DENND1C. Recombinant protein control fragment (Product #RP-99238).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79958
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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