Invitrogen™ DENND4C Monoclonal Antibody (3E8), FITC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545961

Catalog No. PIMA545961

Description

A 1:1,000 dilution of MA5-45961 was sufficient for detection of DENND4C in A549, MEF cells by Western Blot analysis. Detects approximately 213 kDa.

DENND4C is guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.

Specifications

• Antigen: DENND4C
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS, 9.1mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4
• Gene Accession No.: A6H8H2, Q5VZ89
• Gene Symbols: DENND4C
• Immunogen: Full Length Human Recombinant Dennd4c protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 3E8
• Conjugate: FITC
• Gene: DENND4C
• Gene Alias: 1700065A05Rik; AA420392; bA513M16.3; C9orf55; C9orf55B; DENN domain containing 4C; DENN domain-containing protein 4C; DENN domain-containing protein 4C-like protein; DENN/MADD domain containing 4A pseudogene; DENN/MADD domain containing 4C; Dennd4c; likely ortholog of H. sapiens chromosome 9 open reading frame 55 (C9orf55); RAB10GEF; RGD1308489
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 313340, 329877, 55667
• Content And Storage: 4°C, store in dark
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov