Invitrogen™ DENND4C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553279

Catalog No. PIPA553279

Description

Immunogen sequence: ETNRDYSFPA GLEDHILGEN ISPNTSISGL VPSELTQSNT SLGSSSSSGD VGKLHYPTGE VPFPRGMKGQ DFEKSDHGSS QNTSMSSIYQ NCAMEVLMSS CSQCRACGAL VYDEEIMA Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.

DENND4C is guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.

Specifications

• Antigen: DENND4C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DENND4C
• Gene Alias: 1700065A05Rik; AA420392; bA513M16.3; C9orf55; C9orf55B; DENN domain containing 4C; DENN domain-containing protein 4C; DENN domain-containing protein 4C-like protein; DENN/MADD domain containing 4A pseudogene; DENN/MADD domain containing 4C; Dennd4c; likely ortholog of H. sapiens chromosome 9 open reading frame 55 (C9orf55); RAB10GEF; RGD1308489
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55667
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5VZ89
• Gene Symbols: DENND4C
• Immunogen: Recombinant protein corresponding to Human DENND4C. Recombinant protein control fragment (Product #RP-91445).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov