Invitrogen™ DENND4C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA546141

Catalog No. PIPA546141

Description

Peptide sequence: KHNQIITEET GSAVEPSDEI KRASGDVQTM KISSVPNSLS KRNVSLTRSH Sequence homology: Cow: 85%; Dog: 86%; Guinea Pig: 79%; Horse: 85%; Human: 100%; Rabbit: 83%.

DENND4C is guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.

Specifications

• Antigen: DENND4C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DENND4C
• Gene Alias: 1700065A05Rik; AA420392; bA513M16.3; C9orf55; C9orf55B; DENN domain containing 4C; DENN domain-containing protein 4C; DENN domain-containing protein 4C-like protein; DENN/MADD domain containing 4A pseudogene; DENN/MADD domain containing 4C; Dennd4c; likely ortholog of H. sapiens chromosome 9 open reading frame 55 (C9orf55); RAB10GEF; RGD1308489
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55667
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q5VZ89
• Gene Symbols: DENND4C
• Immunogen: Synthetic peptide directed towards the C-terminal of human DENND4C (aa 1590-1639).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov