Invitrogen™ DENND5A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563049

Catalog No. PIPA563049

Description

Immunogen sequence: SALWSHLLHY QDNRQRKLTS GSLSTSGILL DSERRKSDAS SLMPPLRISL IQD Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

DENND5A (DENN domain-containing protein 5A) is a guanine nucleotide exchange factor (GEF) which activates RAB6A and RAB39A/RAB39B. It promotes the exchange of GDP to GTP by converting inactive GDP-bound Rab proteins to their active GTP form. DENND5A is also involved in the negative regulation of neurtie outgrowth. Mutations affecting this gene can result in epileptic encephalopathy, early infantile, 49 (EIEE49).

Specifications

• Antigen: DENND5A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DENND5A
• Gene Alias: 1500012B19Rik; AJ245569; AW496491; DENN domain containing 5A; DENN domain-containing protein 5A; DENN/MADD domain containing 5A; DENND5A; KIAA1091; mKIAA1091; ORF37; Rab6 interacting protein 1; rab6-interacting protein 1; RAB6IP1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23258
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6IQ26
• Gene Symbols: DENND5A
• Immunogen: Recombinant protein corresponding to Human DENND5A. Recombinant protein control fragment (Product #RP-100832).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov