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Invitrogen™ DENND5A Recombinant Rabbit Monoclonal Antibody (14H6L8)

Catalog No. 702789
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70-278-9 100 μg
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Catalog No. 70-278-9 Supplier Invitrogen™ Supplier No. 702789
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Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Mouse, Rat. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

DENND5A (DENN domain-containing protein 5A) is a guanine nucleotide exchange factor (GEF) which activates RAB6A and RAB39A/RAB39B. It promotes the exchange of GDP to GTP by converting inactive GDP-bound Rab proteins to their active GTP form. DENND5A is also involved in the negative regulation of neurtie outgrowth. Mutations affecting this gene can result in epileptic encephalopathy, early infantile, 49 (EIEE49).
TRUSTED_SUSTAINABILITY

Specifications

Antigen DENND5A
Applications Western Blot
Classification Recombinant Monoclonal
Clone 14H6L8
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene DENND5A
Gene Accession No. G3V7Q0, Q6IQ26, Q6PAL8
Gene Alias 1500012B19Rik; AJ245569; AW496491; DENN domain containing 5A; DENN domain-containing protein 5A; DENN/MADD domain containing 5A; DENND5A; KIAA1091; mKIAA1091; ORF37; Rab6 interacting protein 1; rab6-interacting protein 1; RAB6IP1
Gene Symbols DENND5A
Host Species Rabbit
Immunogen Peptide corresponding to human DENND5A [aa828-aa847].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19347, 23258, 308942
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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