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Invitrogen™ DEPDC5 Polyclonal Antibody
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Catalog No. PIPA563150
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100 μL
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PIPA563150 100 μL
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Catalog No. PIPA563150 Supplier Invitrogen™ Supplier No. PA563150
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YDAQVFRLPG PSRAQCLTTC RSVRERESHS RKSASSCDVS SSPSLPSRTL PTEEVRSQAS DDSSLGKSAN ILMIPHPHLH QYEVSSS Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DEPDC5
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DEPDC5
Gene Accession No. O75140
Gene Alias DEP domain containing 5; DEP domain-containing protein 5; DEP.5; DEPD5; DEPDC5; FFEVF; GATOR complex protein DEPDC5; KIAA0645
Gene Symbols DEPDC5
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DEPDC5. Recombinant protein control fragment (Product #RP-95351).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9681
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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