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Invitrogen™ DERL2 Polyclonal Antibody
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Catalog No. PIPA572129
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400 μL
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PIPA572129 400 μL
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Catalog No. PIPA572129 Supplier Invitrogen™ Supplier No. PA572129
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Description

Rabbit Polyclonal Antibody

DERL2 Polyclonal Antibody for Western Blot

Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DERL2
Applications Western Blot
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene DERL2
Gene Accession No. Q8BNI4
Gene Alias carcinoma related; CGI-101; Degradation in endoplasmic reticulum protein 2; Der1-like domain family, member 2; der1-like protein 2; Der2; Derl2; derlin 2; derlin-2; derlin-2-like; DERtrin-2; F-LAN-1; Flana; F-LANa; LOC100910823; SBBI53
Gene Symbols DERL2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 191-219 amino acids from the C-terminal region of mouse Derl2.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116891
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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