Desmin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-3768	Proteintech Group Inc 222051AP150UL	150 μL

Description

Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predomitly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.

Specifications

• Antigen: Desmin
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P17661, P31001, P48675
• Gene ID (Entrez): 13346, 1674, 64362
• Immunogen: Desmin Fusion Protein Ag17525
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DES

• Concentration: 0.27 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CMD1I, CSM1, CSM2, DES, desmin
• Gene Symbols: Des
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody