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Invitrogen™ Desmocollin 2 Polyclonal Antibody
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Catalog No. PIPA547651
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100 μg
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Catalog No. Quantity
PIPA547651 100 μg
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Catalog No. PIPA547651 Supplier Invitrogen™ Supplier No. PA547651
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Description

Sheep Polyclonal Antibody

In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human (rh) Desmocollin-1 and rhDesmocollin-3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Desmocollin 2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene DSC2
Gene Accession No. Q02487
Gene Alias ARVC10; ARVD10; ARVD11; AW228162; Cadherin family member 2; CDHF2; CDHF5; CDHF6; CMD1BB; desmocollin 2; desmocollin-2; Desmocollin-3; desmoglein-2; desmoglein-3; Desmosomal glycoprotein II; desmosomal glycoprotein II/III; Desmosomal glycoprotein III; DG2; DGII/III; DSC2; Dsc2a; Dsc2b; DSC3; Epithelial type 2 desmocollin; HDGC; PVA
Gene Symbols DSC2
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant human Desmocollin-2 Arg136-Arg684.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1824
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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