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Invitrogen™ Desmocollin 2 Polyclonal Antibody
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Catalog No. PIPA582465
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100 μL
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PIPA582465 100 μL
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Catalog No. PIPA582465 Supplier Invitrogen™ Supplier No. PA582465
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KTVIICKPTM SSAEIVAVDP DEPIHGPPFD FSLESSTSEV QRMWRLKAIN DTAARLSYQN DPPFGSYVVP ITVRDRLGMS SVTSLDVTLC DCITENDCTH RVDPRIGGGG VQLGKW Highest antigen sequence indentity to the following orthologs: Rat - 70%, Mouse - 74%.

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Desmocollin 2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DSC2
Gene Accession No. Q02487
Gene Alias ARVC10; ARVD10; ARVD11; AW228162; Cadherin family member 2; CDHF2; CDHF5; CDHF6; CMD1BB; desmocollin 2; desmocollin-2; Desmocollin-3; desmoglein-2; desmoglein-3; Desmosomal glycoprotein II; desmosomal glycoprotein II/III; Desmosomal glycoprotein III; DG2; DGII/III; DSC2; Dsc2a; Dsc2b; DSC3; Epithelial type 2 desmocollin; HDGC; PVA
Gene Symbols DSC2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DSC2. Recombinant protein control fragment (Product #RP-90654).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1824
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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