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Invitrogen™ Desmocollin 2 Polyclonal Antibody
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Catalog No. PIPA587712
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100 μL
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PIPA587712 100 μL
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Catalog No. PIPA587712 Supplier Invitrogen™ Supplier No. PA587712
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IDENTGSIKV FRSLDREAET IKNGIYNITV LASDQGGRTC TGTLGIILQD VNDNSPFIPK KTVIICKPTM SSAEIVAVDP DEPIHGPPFD FSLESSTSEV QRMWRLKAIN DTAARLSYQN DPPFGSYVVP ITVRDRLGMS SVTSLDVTLC DCITENDCTH RVDPRIGGGG V; Positive Samples: A-431, Raji, LO2, BT-474, HT-29; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome.

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Desmocollin 2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.34 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene DSC2
Gene Accession No. Q02487
Gene Alias ARVC10; ARVD10; ARVD11; AW228162; Cadherin family member 2; CDHF2; CDHF5; CDHF6; CMD1BB; desmocollin 2; desmocollin-2; Desmocollin-3; desmoglein-2; desmoglein-3; Desmosomal glycoprotein II; desmosomal glycoprotein II/III; Desmosomal glycoprotein III; DG2; DGII/III; DSC2; Dsc2a; Dsc2b; DSC3; Epithelial type 2 desmocollin; HDGC; PVA
Gene Symbols DSC2
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1824
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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