Invitrogen™ Desmocollin 3 Recombinant Rabbit Monoclonal Antibody (JE55-86)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542507

Catalog No. PIMA542507

Description

Positive Control: Rat skin tissue lysate, A431 cell lysate, 293T, human skin tissue, mouse esophagus tissue, A431. Subcellular Location: Cell membrane, desmosome.

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Specifications

• Antigen: Desmocollin 3
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P55850, Q14574
• Gene Symbols: Dsc3
• Immunogen: Synthetic peptide within C-terminal Human Desmocollin 3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (Paraffin), Western Blot
• Clone: JE55-86
• Conjugate: Unconjugated
• Gene: Dsc3
• Gene Alias: 5430426I24Rik; ARVC10; ARVD10; Cadherin family member 3; CDHF3; CDHF5; CDHF6; CMD1BB; desmocollin 3; desmocollin-3; Desmocollin-4; desmoglein-2; desmoglein-3; DSC; DSC1; DSC2; DSC3; DSC4; HDGC; HT-CP; PVA
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 13507, 1825, 307563
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov