Invitrogen™ Desmoglein 1 Monoclonal Antibody (3G131)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA191590

Catalog No. PIMA191590

Description

Recommended positive controls: Differentiated keratinocytes and Desmoglein 1 transfected cells.

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Specifications

• Antigen: Desmoglein 1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q02413
• Gene Symbols: DSG1
• Immunogen: Intracellular domain of Desmoglein 1 (Human).
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 3G131
• Conjugate: Unconjugated
• Gene: DSG1
• Gene Alias: Cadherin family member 4; CDHF4; desmoglein 1; desmoglein 1 beta; desmoglein 1 gamma; desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG; DSG1; Dsg1b; Dsg1c; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1828
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov