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Invitrogen™ Desmoglein 1 Polyclonal Antibody
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Catalog No. PIPA5121240
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100 μL
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PIPA5121240 100 μL
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Catalog No. PIPA5121240 Supplier Invitrogen™ Supplier No. PA5121240
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Description

Rabbit Polyclonal Antibody

Positive test controls include: A-431, HeLa, 293T, BT-474. The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome. Immunogen sequence: SPHFGTTTVI SESTYPSGPG VLHPKPILDP LGYGNVTVTE SYTTSDTLKP SVHVHDNRPA SNVVVTERVV GPISGADLHG MLEMPDLRDG SNVIVTERVI APSSSLPTSL TIHHPRESSN VVVTERVIQP TSGMIGSLSM HPELANAHNV IVTERVVSGA GVTGISGTTG ISGGIGSSGL VGTSMGAGSG ALSGAGISGG GIGLSSLGGT ASIGHMRSSS DHHFNQTIGS ASPSTARSRI TKYSTVQYSK.

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Desmoglein 1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.67 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DSG1
Gene Accession No. Q02413
Gene Alias Cadherin family member 4; CDHF4; desmoglein 1; desmoglein 1 beta; desmoglein 1 gamma; desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG; DSG1; Dsg1b; Dsg1c; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1
Gene Symbols DSG1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 800-1049 of human DSG1 (NP_001933.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1828, 291755
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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