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Invitrogen™ Desmoglein 4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587952

Catalog No. PIPA587952


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Description

Description

Immunogen sequence: TGTICIEVPD INDYCPNIFP ERRTICIDSP SVLISVNEHS YGSPFTFCVV DEPPGIADMW DVRSTNATSA ILTAKQVLSP GFYEIPILVK DSYNRACELA QMVQLYACDC DDNHMCLDSG AAGIYTEDIT GDTYGPVTED QAGVSNVGLG P; Positive Samples: Mouse pancreas, Rat pancreas, A-375, DU145, BxPC-3, Mouse pancreas, Mouse small intestine; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome.

Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Desmoglein 4
Polyclonal
Unconjugated
DSG4
Cadherin family member 13; CDGF13; CDHF13; desmoglein 4; Desmoglein4; desmoglein-4; DSG4; HYPT6; LAH; lanceolate hair
Rabbit
Affinity Chromatography
RUO
147409, 16769, 291754
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
3.78 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q6W3B0, Q7TMD7, Q86SJ6
DSG4
Recombinant fusion protein containing a sequence corresponding to amino acids 480-630 of human DSG4 (NP_8171231).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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