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Invitrogen™ Desmoglein 4 Polyclonal Antibody
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Catalog No. PIPA587952
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100 μL
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PIPA587952 100 μL
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Catalog No. PIPA587952 Supplier Invitrogen™ Supplier No. PA587952
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TGTICIEVPD INDYCPNIFP ERRTICIDSP SVLISVNEHS YGSPFTFCVV DEPPGIADMW DVRSTNATSA ILTAKQVLSP GFYEIPILVK DSYNRACELA QMVQLYACDC DDNHMCLDSG AAGIYTEDIT GDTYGPVTED QAGVSNVGLG P; Positive Samples: Mouse pancreas, Rat pancreas, A-375, DU145, BxPC-3, Mouse pancreas, Mouse small intestine; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome.

Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Desmoglein 4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.78 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DSG4
Gene Accession No. Q6W3B0, Q7TMD7, Q86SJ6
Gene Alias Cadherin family member 13; CDGF13; CDHF13; desmoglein 4; Desmoglein4; desmoglein-4; DSG4; HYPT6; LAH; lanceolate hair
Gene Symbols DSG4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 480-630 of human DSG4 (NP_8171231).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 147409, 16769, 291754
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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