Invitrogen™ Desmoglein 4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537155

Catalog No. PIPA537155

Description

This antibody detects endogenous protein at a molecular weight of 114 kDa. Purity is >95% by SDS-PAGE.

Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.

Specifications

• Antigen: Desmoglein 4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DSG4
• Gene Alias: Cadherin family member 13; CDGF13; CDHF13; desmoglein 4; Desmoglein4; desmoglein-4; DSG4; HYPT6; LAH; lanceolate hair
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 147409, 16769, 291754
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6W3B0, Q7TMD7, Q86SJ6
• Gene Symbols: DSG4
• Immunogen: A synthetic peptide corresponding to residues in human Desmoglein 4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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