Invitrogen™ Desmoplakin Monoclonal Antibody (DP-2.15)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA183118

Catalog No. PIMA183118

Description

Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 recognizes both desmoplakin 1 and 2 from stratified epithelia, simple epithelia including glands, urothelium, thymic reticular epithelium, hepatocytes, intercalated disks of myocardium and arachnoid cells of meninges. Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 can be used for the detection of primary and metastatic carcinomas.

Desmoplakin (DSP) is a major high molecular weight protein of the desmosomes. It is involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. Desmoplakin mutations are associated with Keratoderma and cardiomyopathy.

Specifications

• Antigen: Desmoplakin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with <0.1% sodium azide; pH 7.4
• Gene Accession No.: E9Q557, P15924
• Gene Symbols: DSP
• Immunogen: Native bovine desmoplakin 1 and 2.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine, Chicken
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Clone: DP-2.15
• Conjugate: Unconjugated
• Gene: DSP
• Gene Alias: 2300002E22Rik; 250/210 kDa paraneoplastic pemphigus antigen; 5730453H04Rik; AA407887; AA407888; AW109828; DCWHKTA; dermatan sulfate proteoglycan 3; desmoplakin; desmoplakin I/II; Desmoplakin II; desmoplakin; LOW QUALITY PROTEIN: desmoplakin; Desmoplakin-I; desmosomal cytoskeletal connector molecule; DP; Dsp; dspg3; Oculoglycan; Opt; Optc; optcl; Opticin; rul; SLRP; SLRP protein; small leucine-rich repeat protein; small leucine-rich repeat protein (SLRP); wu:fb81a05; zgc:101047
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 109620, 1832, 306871, 420869, 514360
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

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