Invitrogen™ Desmoplakin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561103

Catalog No. PIPA561103

Description

Immunogen sequence: NHNKVIETNR ENDKQETWML MELQKIRRQI EHCEGRMTLK NLPLADQGSS HHITVKINEL KSVQNDSQAI AEVLNQLKDM LANFRGSEKY CYLQNEVF Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

Desmoplakin (DSP) is a major high molecular weight protein of the desmosomes. It is involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. Desmoplakin mutations are associated with Keratoderma and cardiomyopathy.

Specifications

• Antigen: Desmoplakin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DSP
• Gene Alias: 2300002E22Rik; 250/210 kDa paraneoplastic pemphigus antigen; 5730453H04Rik; AA407887; AA407888; AW109828; DCWHKTA; dermatan sulfate proteoglycan 3; desmoplakin; desmoplakin I/II; Desmoplakin II; desmoplakin; LOW QUALITY PROTEIN: desmoplakin; Desmoplakin-I; desmosomal cytoskeletal connector molecule; DP; Dsp; dspg3; Oculoglycan; Opt; Optc; optcl; Opticin; rul; SLRP; SLRP protein; small leucine-rich repeat protein; small leucine-rich repeat protein (SLRP); wu:fb81a05; zgc:101047
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1832
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P15924
• Gene Symbols: DSP
• Immunogen: Recombinant protein corresponding to Human Desmoplakin. Recombinant protein control fragment (Product #RP-104081).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG