Invitrogen™ DGAT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA569667

Catalog No. PIPA569667

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.

Specifications

• Antigen: DGAT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DGAT2
• Gene Alias: 0610010B06Rik; Acyl-CoA retinol O-fatty-acyltransferase; ARAT; DGAT2; DGAT-2; diacylglycerol acyltransferase 2; diacylglycerol O-acyltransferase 2; diacylglycerol O-acyltransferase homolog 2; diacylglycerol O-acyltransferase-like protein 2; diglyceride acyltransferase 2; DKFZp686A15125; GS1999FULL; HMFN1045; LOW QUALITY PROTEIN: diacylglycerol O-acyltransferase 2; putative diacylglycerol O-acyltransferase; retinol O-fatty-acyltransferase; UNQ738/PRO1433
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 67800
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9DCV3
• Gene Symbols: DGAT2
• Immunogen: synthetic peptide directed towards the middle region of human DGAT2 (aa 208-257).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov