Invitrogen™ DGCR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530345

Catalog No. PIPA530345

Description

Recommended positive controls: NT2D1, IMR32, MCF-7. Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (80%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.

Specifications

• Antigen: DGCR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DGCR2
• Gene Alias: 9930034O06Rik; Dgcr2; Dgsc; DGS-C; DiGeorge syndrome critical region gene 2; DiGeorge syndrome critical region protein 2; DiGeorge syndrome gene c; DiGeorge syndrome protein C; IDD; integral membrane protein deleted in DiGeorge syndrome; integral membrane protein DGCR2/IDD; KIAA0163; Lan; mKIAA0163; seizure-related membrane-bound adhesion protein; Sez12; Sez-12
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9993
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.48 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P98153
• Gene Symbols: DGCR2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 133 and 361 of Human DGCR2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG