Invitrogen™ DGCR8 Recombinant Rabbit Monoclonal Antibody (3T5Q6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538100

Catalog No. PIMA538100

Description

Positive Samples: HeLa, RD, U-251MG, Mouse brain Immunogen sequence: DLEEFRSYLE KRFDFEQVTV KKFRTWAERR QFNREMKRKQ AESERPILPA NQKLITLSVQ DAPTKKEFVI NPNGKSEVCI LHEYMQRVLK VRPVYNFFEC ENPSEPFGAS VTIDGVTYGS GTASSKKLAK NKAARATLEI LIPDFVKQTS EEKPKDSEEL EYFNHISIED SRVYELTSKA GLLSPYQILH ECLKRNHGMG DTSIKFEVVP GKNQKSEYVM ACGKHTVRGW CKNKRVGKQL ASQKILQLLH PHVKNWGSLL RMYGRESSKM VKQETSDKSV IELQQYAKKN KPNLHILSKL QEEMKRLAEE REETRKKPKM SIVASAQPG.

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: DGCR8
• Classification: Recombinant Monoclonal
• Concentration: 2.1 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8WYQ5, Q9EQM6
• Gene Symbols: DGCR8
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 436-764 of human DGCR8 (Q8WYQ5).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 3T5Q6
• Conjugate: Unconjugated
• Gene: DGCR8
• Gene Alias: C22orf12; D16H22S1742E; D16H22S788E; D16Wis2; DGCR8; DGCR8 microprocessor complex subunit; DGCR8, microprocessor complex subunit; DGCRK6; DiGeorge syndrome critical region 8; diGeorge syndrome critical region 8 homolog; DiGeorge syndrome critical region gene 8; Gy1; LP4941; Microprocessor complex subunit DGCR8; mir-1306; N41; pasha; sb:eu827; sb:eu832; si:ch211-106a19.4; Vo59c07; wu:fc23f08; wu:fc38f06
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54487, 94223
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov