Invitrogen™ DGKA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589555

Catalog No. PIPA589555

Description

Immunogen sequence: MAKERGLISP SDFAQLQKYM EYSTKKVSDV LKLFEDGEMA KYVQGDAIGY EGFQQFLKIY LEVDNVPRHL SLALFQSFET GHCLNETNVT KDVVCLNDVS CYFSLLEGGR PEDKLEFTFK LYDTDRNGIL DSSEVDKIIL QMMRVAEYLD WDVSELRPIL QEMMKEIDYD GSGSVSQAEW VRAGATTVPL LVLLGLEMTL; Positive Samples: NCI-H460, MCF-7, HeLa, Mouse lung, Rat lung.

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Specifications

• Antigen: DGKA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dgka
• Gene Alias: 80 kDa diacylglycerol kinase; 80kDa; AW146112; DAG kinase alpha; Dagk; Dagk1; Dgka; DGK-alpha; diacylglycerol kinase; diacylglycerol kinase alpha; diacylglycerol kinase alpha Flt2-Pr2; diacylglycerol kinase, alpha; diacylglycerol kinase, alpha 80kDa; Diglyceride kinase; diglyceride kinase alpha; MGC12821; MGC42356; truncated diacylglycerol kinase alpha Flt1-Pr1; truncated diacylglycerol kinase alpha Flt1-Pr2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13139, 140866, 1606
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.55 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: O88673, P23743, P51556
• Gene Symbols: Dgka
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DGKA (NP_0013362).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG