DGKI Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-9784	100 μL

Catalog No. 50-198-9784 Supplier Bioss Supplier No. BS14299R

Description

Rabbit Polyclonal Antibody

Diacylglycerol (DAG) influences numerous cell signaling cascades by functioning as an intracellular, allosteric activator of protein kinase C (PKC), and as a potent activator of guanine nucleotide exchange factors. In order to maintain cellular homeostasis, intracellular DAG levels are tightly regulated by diacylglycerol kinases (DGKs, DAGKs), which phosphorylate DAG to phosphatidic acid, thus removing DAG. Human DGK-α (80 kDa), -β (90 kDa), and - γ (90 kDa) have calcium-binding EF-hand motifs at their N termini and are classified as type I DGKs. Human DGK-δ (130 kDa) and DGK-ι (130 kDa) contain N-terminal pleckstrin homology (PH) domains and are classified as type II. Human DGK-epsilon (64 kDa) contains no identifiable regulatory domains and is classified as a type III DGK. Human DGK-Ω (104 kDa) and -iota (130 kDa) possess C-terminal ankyrin repeats and are classified as type IV DGKs. Human DGK-θ (110 kDa) contains 3 cysteine-rich domains and a PH domain and is classified as a type V DGK.

Specifications

• Antigen: DGKI
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH
• Gene: DGKI
• Gene Accession No.: O75912
• Gene Alias: C130010K08Rik; DAG kinase iota; DGKI; DGK-iota; Diacylglycerol kinase iota; diacylglycerol kinase iota-3; diacylglycerol kinase, iota; Diglyceride kinase; Diglyceride kinase iota; EC 2.7.1.107; rDGKi-3
• Gene Symbols: DGKI
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human DGKI.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9162
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG