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Invitrogen™ DGKQ Polyclonal Antibody
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Catalog No. PIPA5101127
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100 μL
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PIPA5101127 100 μL
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Catalog No. PIPA5101127 Supplier Invitrogen™ Supplier No. PA5101127
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total DAGK.

Diacylglycerol (DAG) is a fundamental lipid second messenger that is produced in the nucleus. The accumulation of DAG in the nucleus is important for the regulation of cell growth and differentiation. Diacylglycerol kinases (DGKs) convert DAG to phosphatidic acid, thereby terminating diacylglycerol signaling, which results in the reduction of protein kinase C activity and cell cycle progression of T lymphocytes. Diacylglycerol kinases are divided into five subtypes, Type I-Type V. DGK-theta is a Type V DGK, and localizes mainly to the nucleus of various cell lines, such as MDA-MB-453, MCF-7, PC12 and HeLa. Nuclear DGK-theta co-localizes with phosphatidylinositol 4, 5-bisphosphate (PIP(2)). DGK-theta is the isoform responsive to alpha-Thrombin stimulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DGKQ
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DGKQ
Gene Accession No. P52824, Q6P5E8
Gene Alias 110kDa; DAG kinase theta; DAGK; Dagk4; DAGK7; Dgk theta; Dgkd; DGKQ; DGK-theta; Diacylglycerol kinase theta; diacylglycerol kinase, delta (110 kDa); diacylglycerol kinase, theta; diacylglycerol kinase, theta 110kDa; diglyceride kinase theta; testis tissue sperm-binding protein Li 38a
Gene Symbols DGKQ
Host Species Rabbit
Immunogen A synthesized peptide derived from human DGKQ(Accession P52824), corresponding to amino acid residues Q800-V850.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110524, 1609
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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