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Invitrogen™ DHCR24 Polyclonal Antibody
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Catalog No. PIPA527944
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100 μL
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PIPA527944 100 μL
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Catalog No. PIPA527944 Supplier Invitrogen™ Supplier No. PA527944
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, H1299, mouse brain. Predicted reactivity: Mouse (95%), Rat (95%), Zebrafish (82%), Xenopus laevis (81%), Pig (95%), Chicken (80%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DHCR24
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Dhcr24
Gene Accession No. Q15392, Q5BQE6
Gene Alias 2310076D10Rik; 24-dehydrocholesterol reductase; 3 beta-hydroxysterol delta 24-reductase; 3-beta-hydroxysterol delta-24 reductase; 3-beta-hydroxysterol delta-24-reductase; 5830417J06Rik; DCE; Delta(24)-sterol reductase; desmosterol-to-cholesterol enzyme; DHCR24; Diminuto/dwarf1 homolog; KIAA0018; mKIAA0018; Nbla03646; seladin 1; SELADIN1; seladin-1; selective AD indicator 1
Gene Symbols Dhcr24
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Seladin 1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1718, 298298
Target Species Human, Rat, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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