Invitrogen™ DHFR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530992

Catalog No. PIPA530992

Description

Recommended positive controls: 293T, A431, PC-12. Predicted reactivity: Mouse (88%), Rat (89%), Pig (88%), Bovine (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, and is required for the synthesis of purines, thymidylic acid and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.

Specifications

• Antigen: DHFR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DHFR
• Gene Alias: 8430436I03Rik; AA607882; AI662710; AW555094; Dhfr; Dhfr1; DHFRP1; Dihydrofolate reductase; Dihydrofolate reductase 1 (active); DYR
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1719, 24312
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.54 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P00374, Q920D2
• Gene Symbols: DHFR
• Immunogen: Recombinant protein encompassing a sequence within the center region of human DHFR. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov