Invitrogen™ DHFR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579152

Catalog No. PIPA579152

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human Jurkat whole cell, rat liver tissue, rat kidney tissue, mouse liver tissue, mouse kidney tissue. IHC: human colorectal cancer tissue, mouse small intestine tissue, rat small intestine tissue. ICC/IF: U20S cell. Flow: PC-3 cell.

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, and is required for the synthesis of purines, thymidylic acid and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.

Specifications

• Antigen: DHFR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DHFR
• Gene Alias: 8430436I03Rik; AA607882; AI662710; AW555094; Dhfr; Dhfr1; DHFRP1; Dihydrofolate reductase; Dihydrofolate reductase 1 (active); DYR
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13361, 1719, 24312
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.01mg sodium azide
• Gene Accession No.: P00374, P00375, Q920D2
• Gene Symbols: DHFR
• Immunogen: E.coli-derived human DHFR recombinant protein (Position: V2-D187).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov