Invitrogen™ DHH Monoclonal Antibody (2G5)

Catalog No.	Quantity
PIMA521835	100 μg

Catalog No. PIMA521835 Supplier Invitrogen™ Supplier No. MA521835

Description

Mouse Monoclonal Antibody

Peptide Sequence: SGERKGLREL HRGDWVLAAD ASGRVVPTPV LLFLDRDLQR RASFVAVETE WPPRKLLLTP WHLVFAARGP APAPGDFAPV FARRLRAGDS VLAPGGDALR P*.

This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signaling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Specifications

• Antigen: DHH
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 2G5
• Concentration: 0.2-1.0 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: Dhh
• Gene Accession No.: O43323
• Gene Alias: C78960; desert hedgehog; desert hedgehog protein; Desert hedgehog protein C-product; Desert hedgehog protein N-product; Dhh; GDXYM; HHG-3; SRXY7
• Gene Symbols: Dhh
• Host Species: Mouse
• Immunogen: DHH (NP_066382, 210 a.a. ~ 310 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 50846
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a κ