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Invitrogen™ DHH Polyclonal Antibody
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Catalog No. PIPA5109633
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100 μL
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PIPA5109633 100 μL
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Catalog No. PIPA5109633 Supplier Invitrogen™ Supplier No. PA5109633
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CFPGNATVRL WSGERKGLRE LHRGDWVLAA DASGRVVPTP VLLFLDRDLQ RRASFVAVET EWPPRKLLLT PWHLVFAARG PAPAPGDFAP VFARRLRAGD SVLAPGGDAL RPARVARVAR EEAVGVFAPL TAHGTLLVND VLASCYAVLE SHQWAHRAFA PLRLLHALGA LLPGGAVQPT GMHWYSRLLY RLAEELLG.

This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signaling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DHH
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Dhh
Gene Accession No. O43323, Q61488
Gene Alias C78960; desert hedgehog; desert hedgehog protein; Desert hedgehog protein C-product; Desert hedgehog protein N-product; Dhh; GDXYM; HHG-3; SRXY7
Gene Symbols Dhh
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 199-396 of human DHH (NP_066382.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13363, 50846, 84380
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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